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Polymyositis and the associated inflammatory myopathies have an associated increased risk of cancer. [3] The features they found associated with an increased risk of cancer were older age, age greater than 45, male sex, difficulty swallowing, death of skin cells, cutaneous vasculitis, rapid onset of myositis (<4 weeks), elevated creatine kinase, higher erythrocyte sedimentation rate and higher ...
Infection - The most common infectious cause of myositis is viral infections, such as the common cold. [4] Other viruses, such as COVID-19, are also shown to be a rare cause of myositis. [6] Benign acute childhood myositis has been described in children after prodromal viral infections with different viral agents.
It can also be associated with underlying cancer. The main classes of idiopathic inflammatory myopathy are polymyositis (PM), dermatomyositis (DM) (including juvenile, amyopathic, and sine-dermatitis form), inclusion-body myositis (IBM), immune-mediated necrotising myopathy (IMNM), and focal autoimmune myositis. [1]
Complications may include calcium deposits in muscles or skin. [1] The cause is unknown. [1] Theories include that it is an autoimmune disease or a result of a viral infection. [1] Dermatomyositis may develop as a paraneoplastic syndrome associated with several forms of malignancy. [4] It is a type of inflammatory myopathy. [1]
It manifests itself in children; it is the pediatric counterpart of dermatomyositis. In JDM, the body's immune system attacks blood vessels throughout the body, causing inflammation called vasculitis. In the United States, the incidence rate of JDMS is approximately 2-3 cases per million children per year. The UK incidence is believed to be ...
Polymyositis produces muscle weakness. It can often be treated by drugs like corticosteroids or immunosuppressants. It can often be treated by drugs like corticosteroids or immunosuppressants. Inclusion body myositis is a slowly progressive disease that produces weakness of hand grip and straightening of the knees.
IBM is often confused with (misdiagnosed as) polymyositis. Polymyositis that does not respond to treatment is likely IBM. [35] Dermatomyositis shares a number of similar physical symptoms and histopathological traits as polymyositis, but exhibits a skin rash not seen in polymyositis or sIBM. It may have different root causes unrelated to either ...
Globally, about 3 million children and young adults are impacted by this disease. [37] In the US it affects about 250,000-294,000 children making it one of the most common groups of childhood diseases. [12] However, due to not having consistent guidelines or criteria for diagnosis, this number is an estimation based on smaller population groups ...