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The median effective dose is the dose that produces a quantal effect (all or nothing) in 50% of the population that takes it (median referring to the 50% population base). [6] It is also sometimes abbreviated as the ED 50, meaning "effective dose for 50% of the population". The ED50 is commonly used as a measure of the reasonable expectancy of ...
Functional capacity can also be expressed as "METs" and can be used as a reliable predictor of future cardiac events. [5] One MET is defined as the amount of oxygen consumed while sitting at rest, and is equal to 3.5 ml oxygen per kilogram body weight per minute.
Drugs come with a recommended dose in milligrams or micrograms per kilogram of body weight, and that is used in conjunction with the patient's age and body weight to determine a safe dose. In single-dose scenarios, the patient's body weight and the drug's recommended dose per kilogram are used to determine a safe one-time dose.
It is the minimum dose or concentration of a drug that produces a biological response in 50% of a population being studied. Median lethal dose: For either drugs or toxins, it is a toxic unit that measures the minimum dose that causes death (lethal dose) in 50% of cases. Median toxic dose
In pharmacokinetics, a maintenance dose is the maintenance rate [mg/h] of drug administration equal to the rate of elimination at steady state. This is not to be confused with dose regimen , which is a type of drug therapy in which the dose [mg] of a drug is given at a regular dosing interval on a repetitive basis.
The feeding at all places is done by means of small capacity dosing pumps specially designed for the duty demanded. In building services the water quality of various pumped fluid systems, including for heating, cooling, and condensate water, will be regularly checked and topped up with chemicals manually as required to suit the required water ...
The absorbed dose required to produce a certain biological effect varies between different types of radiation, such as photons, neutrons or alpha particles. This is taken into account by the equivalent dose (H), which is defined as the mean dose to organ T by radiation type R (D T,R), multiplied by a weighting factor W R.
Functional residual capacity (FRC) is the volume of air present in the lungs at the end of passive expiration. [1] At FRC, the opposing elastic recoil forces of the lungs and chest wall are in equilibrium and there is no exertion by the diaphragm or other respiratory muscles.