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  2. Bioconcentration - Wikipedia

    en.wikipedia.org/wiki/Bioconcentration

    [15] k 1 is the rate constant for chemical uptake from water at the respiratory surface (L*kg −1 *d −1). [15] C WD is the chemical concentration dissolved in water (g*L −1). [15] k 2,k E,k G,k B are rate constants that represent excretion from the organism from the respiratory surface, fecal excretion, metabolic transformation, and growth ...

  3. Fluid balance - Wikipedia

    en.wikipedia.org/wiki/Fluid_balance

    The recommended daily amount of drinking water for humans varies. [1] It depends on activity, age, health, and environment.In the United States, the Adequate Intake for total water, based on median intakes, is 4.0 litres (141 imp fl oz; 135 US fl oz) per day for males older than 18, and 3.0 litres (106 imp fl oz; 101 US fl oz) per day for females over 18; it assumes about 80% from drink and 20 ...

  4. Dissociation constant - Wikipedia

    en.wikipedia.org/wiki/Dissociation_constant

    The concentration of water, [H 2 O], is omitted by convention, which means that the value of K w differs from the value of K eq that would be computed using that concentration. The value of K w varies with temperature, as shown in the table below. This variation must be taken into account when making precise measurements of quantities such as pH.

  5. Henderson–Hasselbalch equation - Wikipedia

    en.wikipedia.org/wiki/Henderson–Hasselbalch...

    The Henderson–Hasselbalch equation can be used to model these equilibria. It is important to maintain this pH of 7.4 to ensure enzymes are able to work optimally. [10] Life threatening Acidosis (a low blood pH resulting in nausea, headaches, and even coma, and convulsions) is due to a lack of functioning of enzymes at a low pH. [10]

  6. Equilibrium constant - Wikipedia

    en.wikipedia.org/wiki/Equilibrium_constant

    The stepwise constant, K, for the formation of the same complex from ML and L is given by ML + L ⇌ ML 2; [ML 2] = K[ML][L] = Kβ 11 [M][L] 2. It follows that β 12 = Kβ 11. A cumulative constant can always be expressed as the product of stepwise constants. There is no agreed notation for stepwise constants, though a symbol such as K L

  7. Protein pKa calculations - Wikipedia

    en.wikipedia.org/wiki/Protein_pKa_calculations

    The pH-dependence of the activity displayed by enzymes and the pH-dependence of protein stability, for example, are properties that are determined by the pK a values of amino acid side chains. The p K a values of an amino acid side chain in solution is typically inferred from the p K a values of model compounds (compounds that are similar to ...

  8. Acid dissociation constant - Wikipedia

    en.wikipedia.org/wiki/Acid_dissociation_constant

    At half-neutralization the ratio ⁠ [A −] / [HA] ⁠ = 1; since log(1) = 0, the pH at half-neutralization is numerically equal to pK a. Conversely, when pH = pK a, the concentration of HA is equal to the concentration of A −. The buffer region extends over the approximate range pK a ± 2. Buffering is weak outside the range pK a ± 1.

  9. Acid–base titration - Wikipedia

    en.wikipedia.org/wiki/Acid–base_titration

    = = Where K b is the base dissociation constant, K w is the water dissociation constant. 4. The pH after the equivalence point depends on the concentration of the conjugate base of the weak acid and the strong base of the titrant. However, the base of the titrant is stronger than the conjugate base of the acid. Therefore, the pH in this region ...