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Caseous lymphadenitis (CLA) is an infectious disease caused by the bacterium Corynebacterium pseudotuberculosis, that affects the lymphatic system, resulting in abscesses in the lymph nodes and internal organs. It is found mostly in goats and sheep and at the moment it has no cure. [1]
C. pseudotuberculosis causes a disease known as caseous lymphadenitis that most commonly affects small ruminants, such as goats and sheep. [9] [10] The disease often presents with pyogranulomatous abscess formation. [11] Abscessation can occur in numerous areas, but it most commonly affects the cutaneous region and superficial lymph nodes.
Sheep and goats are both small ruminants with cosmopolitan distributions due to their being kept historically and in modern times as grazers both individually and in herds in return for their production of milk, wool, and meat. [1] As such, the diseases of these animals are of great economic importance to humans.
Hyperchloremia is an electrolyte disturbance in which there is an elevated level of chloride ions in the blood. [1] The normal serum range for chloride is 96 to 106 mEq/L, [2] therefore chloride levels at or above 110 mEq/L usually indicate kidney dysfunction as it is a regulator of chloride concentration. [3]
Cattle, sheep, goat, and other ruminants that are diagnosed with PEM or pre-PEM suffer opisthotonus, cortical blindness, disoriented movement, and eventually fatality, if left untreated. [1] Current data shows that the onset of PEM can range from birth to late adulthood.
GOAT, which stands for "Greatest Of All Time," is the ultimate compliment of all compliments. While the acronym can be applied to describe any Decoded: What GOAT means and how to use it
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The clinical signs are similar in other ruminants. In sheep and goats, the wool or hair is often damaged and easily shed, and diarrhea is uncommon. In deer, paratuberculosis can progress rapidly. Intestinal disease has also been reported in rabbits and nonhuman primates. [citation needed]