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To date, most sleep deprivation studies have focused on acute sleep deprivation, suggesting that acute sleep deprivation can cause significant damage to cognitive, emotional, and physical functions and brain mechanisms. [11] Few studies have compared the effects of acute total sleep deprivation and chronic partial sleep restriction. [8]
Sleep deprivation may additionally affect memory by reducing the proliferation of cells in the hippocampus. [51] Sleep deprivation has also been associated with decreased overall membrane excitability of neurons in the brain. Activation of these membranes is critical for the formation of memories. [52]
Sleep deprivation has been found to affect mood as well. [47] This effect is most pronounced in those that are consistently partially sleep deprived, which is the case for many college students. A meta-analysis of several studies regarding sleep deprivation suggests that the effects of partial sleep deprivation are underestimated.
Observations have been made that there is an association between stress, sleep, and Interleukin-6 proposing a possible mechanism for sleep changes. During both chronic and acute phase sleep deprivation, there are increases in the pro-inflammatory cytokine Interleukin-6 (IL-6).
Sleep deprivation is common and sometimes even necessary in modern societies because of occupational and domestic reasons like round-the-clock service, security or media coverage, cross-time-zone projects etc. This makes understanding the effects of sleep deprivation very important. Many studies have been done from the early 1900s to document ...
Deficient sleep patterns are prominent in many psychiatric ailments. [18] Insomnia increases the risk of a depressive episode, sleep deprivation influences the onset of hypomania, and sleep disturbance contributes to the maintenance of mood disorders. [19] Amongst manic bipolar patients, sleep loss may act as a trigger in the onset of a manic ...
A large sleep debt may lead to mental or physical fatigue, and can adversely affect one's mood, energy, and ability to think clearly. There are two kinds of sleep debt: the result of partial sleep deprivation, and of total sleep deprivation. Partial sleep deprivation occurs when a person or a lab animal sleeps too little for several days or ...
Sleep disturbances often occur before the onset of psychosis. Sleep deprivation can also produce hallucinations, delusions and depression. [26] A 2019 study investigated the three above-mentioned sleep disturbances in schizophrenia-spectrum (SCZ) and bipolar (BP) disorders in 617 SCZ individuals, 440 BP individuals, and 173 healthy controls (HC).