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Rare side effects may include high potassium levels and blood clots (when taken as a combined oestrogen-progestogen pill), among others. [ 4 ] [ 12 ] Drospirenone is a progestin, or a synthetic progestogen , and hence is an agonist of the progesterone receptor , the biological target of progestogens like progesterone . [ 1 ]
Each box, as supplied by the manufacturer, contains three blister packs of 28 tablets packaged in individual boxes. Each blister pack of 28 tablets contains 24 pink active pills containing drospirenone 3 mg, ethinylestradiol 20 mcg, and levomefolate calcium 0.451 mg and four light orange inactive pills containing levomefolate calcium 0.451 mg. [7] [9]
[2] [3] A formulation with levomefolic acid (vitamin B 9) has also been marketed (brand names Beyaz, Safyral, others), with similar indications. [7] [8] EE/DRSP is marketed widely throughout the world. [9] In 2022, it was the 142nd most commonly prescribed medication in the United States, with more than 4 million prescriptions. [10] [11]
The high water solubility of estetrol makes it optimal for passage of the blood–brain barrier, and the drug may be expected to have effects in the central nervous system. [2] In accordance, estetrol shows clear central effects such as alleviation of hot flashes and antigonadotropic effects in humans.
GLP-1 drugs for weight loss and type 2 diabetes include dulaglutide, liraglutide, and semaglutide. GIP/GLP-1s. These are dual-acting, meaning they target two receptors in the body: gastric ...
A recent study has shown that people who take SGLT-2 inhibitors for type 2 diabetes management have a 35% lower diabetes risk, overall. A diabetes drug may help prevent dementia, new research ...
Estradiol/drospirenone (E2/DRSP), sold under the brand name Angeliq, is a combination of estradiol (E2), an estrogen, and drospirenone (DRSP), a progestin, antimineralocorticoid, and antiandrogen, which is used in menopausal hormone therapy, specifically the treatment of menopausal syndrome and osteoporosis, in postmenopausal women.
Drospirenone/estetrol, sold under the brand name Nextstellis, among others, is a fixed-dose combination medication containing drospirenone, a progestin, and estetrol, an estrogen, which is used as a combined birth control pill for the prevention of pregnancy in women. [2] [6] It is taken by mouth. [2] [6]
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