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Cushing reflex (also referred to as the vasopressor response, the Cushing effect, the Cushing reaction, the Cushing phenomenon, the Cushing response, or Cushing's Law) is a physiological nervous system response to increased intracranial pressure (ICP) that results in Cushing's triad of increased blood pressure, irregular breathing, and bradycardia. [1]
Intracranial pressure (ICP) is the pressure exerted by fluids such as cerebrospinal fluid (CSF) inside the skull and on the brain tissue. ICP is measured in millimeters of mercury and at rest, is normally 7–15 mmHg for a supine adult. This equals to 9–20 cmH 2 O, which is a common scale used in lumbar punctures. [1]
A Cushing ulcer, named after Harvey Cushing, [1] [2] is a gastric ulcer associated with elevated intracranial pressure. It is also called von Rokitansky –Cushing syndrome. [ 2 ] Apart from the stomach , ulcers may also develop in the proximal duodenum and distal esophagus .
Cushing reflex - triad of hypertension, bradycardia, and irregular breathing in response to elevated ICP. Diving reflex; Enterogastric reflex; Galant reflex — a primitive reflex in infants up to four months of age, a rotation of the upper body towards one or other side of the back when that side is stroked. Glabellar reflex; Golgi tendon reflex
Brain herniation is a potentially deadly side effect of very high pressure within the skull that occurs when a part of the brain is squeezed across structures within the skull. The brain can shift across such structures as the falx cerebri , the tentorium cerebelli , and even through the foramen magnum (the hole in the base of the skull through ...
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Additional risks presented to patients can include high costs associated with an ICP sensor's implantation procedure, and the limited access to trained personnel, e.g. a neurosurgeon. Alternative, non-invasive measurement of intracranial pressure, non-invasive methods for estimating ICP have, as a result, been sought. [2]
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