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Tabes dorsalis is a late consequence of neurosyphilis, characterized by the slow degeneration (specifically, demyelination) of the neural tracts primarily in the dorsal root ganglia of the spinal cord (nerve root). These patients have lancinating nerve root pain which is aggravated by coughing, and features of sensory ataxia with ocular ...
Abadie's sign of tabes dorsalis is a medical sign of tabes dorsalis, a late consequence of neurosyphilis. It is elicited by compressing the Achilles tendon , which normally causes pain. A positive Abadie's sign is defined by the absence of pain.
Joseph Louis Irenée Jean Abadie was born in 1873 in Tarbes, département Hautes-Pyrénées, France.He studied medicine at the University of Bordeaux, qualifying in 1900.
Tabes dorsalis is a form of late neurosyphilis that affects the posterior columns of the spinal cord. Parenchymal syphilis occurs in the late stage of neurosyphilis, with average presentation occurring 15 to 25 years after initial infection. [3] This stage of the disease is generally in the form of tabes dorsalis or general paresis.
Conditions affecting the dorsal columns of the spinal cord, such as tabes dorsalis (neurosyphilis), in which it was first described. [1] Conditions affecting the sensory nerves (sensory peripheral neuropathies), such as chronic inflammatory demyelinating polyradiculoneuropathy . Friedreich's ataxia; Ménière's disease
Hutchinson's mask is a patient's sensation that the face is covered with a mask or a gauzy network like cobwebs. This medical sign is associated with tabes dorsalis [1] affecting the trigeminal nerve (fifth cranial nerve CN V).
General paresis, also known as general paralysis of the insane (GPI), paralytic dementia, or syphilitic paresis is a severe neuropsychiatric disorder, classified as an organic mental disorder, and is caused by late-stage syphilis and the chronic meningoencephalitis and cerebral atrophy that are associated with this late stage of the disease when left untreated.
The control of syphilis in the United Kingdom began with the 1916 report of a Royal Commission on Venereal Diseases. Clinics were established offering testing and education. This caused a fall in the prevalence of syphilis, leading to almost a halving of tabes dorsalis between 1914 and 1936.