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  2. Sirolimus - Wikipedia

    en.wikipedia.org/wiki/Sirolimus

    Sirolimus, also known as rapamycin and sold under the brand name Rapamune among others, is a macrolide compound that is used to coat coronary stents, prevent organ transplant rejection, treat a rare lung disease called lymphangioleiomyomatosis, and treat perivascular epithelioid cell tumour (PEComa).

  3. mTOR inhibitors - Wikipedia

    en.wikipedia.org/wiki/MTOR_inhibitors

    mTOR inhibitors are a class of drugs used to treat several human diseases, including cancer, autoimmune diseases, and neurodegeneration. They function by inhibiting the mammalian target of rapamycin (mTOR) (also known as the mechanistic target of rapamycin), which is a serine/threonine-specific protein kinase that belongs to the family of phosphatidylinositol-3 kinase (PI3K) related kinases ...

  4. Immunosuppressive drug - Wikipedia

    en.wikipedia.org/wiki/Immunosuppressive_drug

    Sirolimus (rapamycin, trade name Rapamune) is a macrolide lactone, produced by the actinomycete bacterium Streptomyces hygroscopicus. It is used to prevent rejection reactions. Although it is a structural analogue of tacrolimus, it acts somewhat differently and has different side-effects.

  5. The Terrible—and Amazing—Side Effects of Weight-Loss Drugs

    www.aol.com/terrible-amazing-side-effects-weight...

    GLP-1 drugs used for weight loss involve all kinds of side effects—good and not-so-good—that may or may not strike the average user. (Reminder that there are many of these meds now.

  6. Surendra Nath Sehgal - Wikipedia

    en.wikipedia.org/wiki/Surendra_Nath_Sehgal

    Surendra Nath Sehgal (1932–2003) was an Indian-Canadian-American microbiologist and pharmaceutical scientist most widely known for his discovery and development of Rapamycin (Sirolimus), a immunosuppressant drug widely used in organ transplantation. Rapamycin has also attracted attention as a potential anti-cancer [1] and anti-aging drug. [2]

  7. 6 Common Side Effects from Taking a GLP-1 Medication ... - AOL

    www.aol.com/6-common-side-effects-taking...

    These side effects might be common, but there are things you can do if they’re impacting your daily life. 6 Common Side Effects from Taking a GLP-1 Medication—and How to Manage Them Skip to ...

  8. Everolimus - Wikipedia

    en.wikipedia.org/wiki/Everolimus

    Everolimus, sold under the brand name Afinitor among others, is a medication used as an immunosuppressant to prevent rejection of organ transplants [10] and as a targeted therapy in the treatment of renal cell cancer and other tumours. [11] This compound also has a use in cardiovascular drug-eluting stent technologies to inhibit restenosis.

  9. mTOR - Wikipedia

    en.wikipedia.org/wiki/MTOR

    The mammalian target of rapamycin (mTOR), [5] also referred to as the mechanistic target of rapamycin, and sometimes called FK506-binding protein 12-rapamycin-associated protein 1 (FRAP1), is a kinase that in humans is encoded by the MTOR gene.

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