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The Radiometer Corporation of Denmark was founded in 1935, and began marketing a pH meter for medical use around 1936, but "the development of automatic pH-meters for industrial purposes was neglected. Instead American instrument makers successfully developed industrial pH-meters with a wide variety of applications, such as in breweries, paper ...
Also acid ionization constant or acidity constant. A quantitative measure of the strength of an acid in solution expressed as an equilibrium constant for a chemical dissociation reaction in the context of acid-base reactions. It is often given as its base-10 cologarithm, p K a. acid–base extraction A chemical reaction in which chemical species are separated from other acids and bases. acid ...
The electrode potential is proportional to pH when pH is defined in terms of activity. The precise measurement of pH is presented in International Standard ISO 31-8 as follows: [ 15 ] A galvanic cell is set up to measure the electromotive force (e.m.f.) between a reference electrode and an electrode sensitive to the hydrogen ion activity when ...
In gastroenterology, esophageal pH monitoring is the current gold standard for diagnosis of gastroesophageal reflux disease (GERD). It provides direct physiologic measurement of acid in the esophagus and is the most objective method to document reflux disease, assess the severity of the disease and monitor the response of the disease to medical or surgical treatment.
H + does not cross through the glass membrane of the pH electrode, it is the Na + which crosses and leads to a change in free energy. When an ion diffuses from a region of activity to another region of activity, there is a free energy change and this is what the pH meter actually measures.
Instrument Uses Test tube: Folin-Wu tube: Glass slide mycole and cover slips: in microscopy, serology, etc. as the solid backing on which test samples are : Petri dish: used for preparation of culture media and the culture of organisms they are in
In and of themselves, pH indicators are usually weak acids or weak bases. The general reaction scheme of acidic pH indicators in aqueous solutions can be formulated as: HInd (aq) + H 2 O (l) ⇌ H 3 O + (aq) + Ind − (aq) where, "HInd" is the acidic form and "Ind −" is the conjugate base of the indicator. Vice versa for basic pH indicators ...
[21]: 119–124 For example, stabilizing agents such as antioxidants or antimicrobial agents may be added to prevent degradation, liquids containing certified concentrations of trace metals may have pH adjusted to keep metals in solution, and clinical reference materials may be freeze-dried for long term storage if they can be reconstituted ...