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  2. Nucleotide base - Wikipedia

    en.wikipedia.org/wiki/Nucleotide_base

    The purine nitrogenous bases are characterized by their single amino group (−NH 2), at the C6 carbon in adenine and C2 in guanine. [5] Similarly, the simple-ring structure of cytosine, uracil, and thymine is derived of pyrimidine, so those three bases are called the pyrimidine bases. [6]

  3. Cytosine - Wikipedia

    en.wikipedia.org/wiki/Cytosine

    Cytosine (/ ˈ s aɪ t ə ˌ s iː n,-ˌ z iː n,-ˌ s ɪ n / [2] [3]) (symbol C or Cyt) is one of the four nucleotide bases found in DNA and RNA, along with adenine, guanine, and thymine (uracil in RNA). It is a pyrimidine derivative, with a heterocyclic aromatic ring and two substituents attached (an amine group at position 4 and a keto group ...

  4. Nucleic acid structure - Wikipedia

    en.wikipedia.org/wiki/Nucleic_acid_structure

    Cytosine, thymine, and uracil are pyrimidines, hence the glycosidic bonds form between their 1 nitrogen and the 1' -OH of the deoxyribose. For both the purine and pyrimidine bases, the phosphate group forms a bond with the deoxyribose sugar through an ester bond between one of its negatively charged oxygen groups and the 5' -OH of the sugar. [2]

  5. Uracil - Wikipedia

    en.wikipedia.org/wiki/Uracil

    Uracil is also involved in the biosynthesis of polysaccharides and the transportation of sugars containing aldehydes. [22] Uracil is important for the detoxification of many carcinogens, for instance those found in tobacco smoke. [23] Uracil is also required to detoxify many drugs such as cannabinoids (THC) [24] and morphine (opioids). [25]

  6. Wobble base pair - Wikipedia

    en.wikipedia.org/wiki/Wobble_base_pair

    Wobble base pairs for inosine and guanine. A wobble base pair is a pairing between two nucleotides in RNA molecules that does not follow Watson-Crick base pair rules. [1] The four main wobble base pairs are guanine-uracil (G-U), hypoxanthine-uracil (I-U), hypoxanthine-adenine (I-A), and hypoxanthine-cytosine (I-C).

  7. CpG site - Wikipedia

    en.wikipedia.org/wiki/CpG_site

    CpG is shorthand for 5'—C—phosphate—G—3' , that is, cytosine and guanine separated by only one phosphate group; phosphate links any two nucleosides together in DNA. . The CpG notation is used to distinguish this single-stranded linear sequence from the CG base-pairing of cytosine and guanine for double-stranded sequenc

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  9. Bisulfite sequencing - Wikipedia

    en.wikipedia.org/wiki/Bisulfite_sequencing

    Figure 2: Outline of the chemical reaction that underlies the bisulfite-catalyzed conversion of cytosine to uracil. Bisulfite [ 1 ] sequencing (also known as bisulphite sequencing ) is the use of bisulfite treatment of DNA before routine sequencing to determine the pattern of methylation .