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Heat stress can result in heat-related illnesses, such as heat stroke, hyperthermia, heat exhaustion, heat cramps, heat rashes, and chronic kidney disease (CKD). [2] [3] Although heat exhaustion is less severe, heat stroke is a medical emergency and requires emergency treatment, which if not provided, can lead to death. [4]
Simplified control circuit of human thermoregulation. [8]The core temperature of a human is regulated and stabilized primarily by the hypothalamus, a region of the brain linking the endocrine system to the nervous system, [9] and more specifically by the anterior hypothalamic nucleus and the adjacent preoptic area regions of the hypothalamus.
An early stage of hyperthermia can be "heat exhaustion" (or "heat prostration" or "heat stress"), whose symptoms can include heavy sweating, rapid breathing and a fast, weak pulse. If the condition progresses to heat stroke, then hot, dry skin is typical [ 2 ] as blood vessels dilate in an attempt to increase heat loss.
Heat illness is a spectrum of disorders due to increased body temperature. It can be caused by either environmental conditions or by exertion. It includes minor conditions such as heat cramps, heat syncope, and heat exhaustion as well as the more severe condition known as heat stroke. [1] It can affect any or all anatomical systems. [2]
A reduction in stroke volume is the decline in the volume of blood the heart is circulating, reducing the heart’s cardiac output. [6] The stroke volume is reduced due to loss of fluids in the body, reducing the volume of blood in the body. [7] This leads the increase in heart rate to compensate for the reduced cardiac output during exercise. [6]
Heat syncope is fainting or dizziness as a result of overheating (syncope is the medical term for fainting). It is a type of heat illness. The basic symptom of heat syncope is fainting, with or without mental confusion. [1] Heat syncope is caused by peripheral vessel dilation, resulting in diminished blood flow to the brain and dehydration.
Heat stroke is defined by two key features: a core body temperature above 40 °C (104 °F) and central nervous system dysfunction. In classic heat stroke, sweating ceases due to sweat gland dysfunction or depletion. This loss of evaporative cooling further accelerates heat accumulation.
Heatstroke is a life-threatening condition due to the potential for multi-organ dysfunction, [6] with typical complications including seizures, rhabdomyolysis, or kidney failure. [3] Heat stroke occurs because of high external temperatures and/or physical exertion.