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  2. Lac repressor - Wikipedia

    en.wikipedia.org/wiki/Lac_repressor

    The repressor is shown in complex with operator DNA (gold) and ONPF (green), an anti-inducer ligand (i.e. a stabilizer of DNA binding) The lac repressor (LacI) is a DNA-binding protein that inhibits the expression of genes coding for proteins involved in the metabolism of lactose in bacteria. These genes are repressed when lactose is not ...

  3. β-Galactosidase - Wikipedia

    en.wikipedia.org/wiki/Β-Galactosidase

    Function. β-Galactosidase is an exoglycosidase which hydrolyzes the β- glycosidic bond formed between a galactose and its organic moiety. It may also cleave fucosides and arabinosides but at a much lower rate. It is an essential enzyme in the human body. Deficiencies in the protein can result in galactosialidosis or Morquio B syndrome.

  4. Muscular system - Wikipedia

    en.wikipedia.org/wiki/Muscular_system

    The muscular system is an organ system consisting of skeletal, smooth, and cardiac muscle. It permits movement of the body, maintains posture, and circulates blood throughout the body. [1] The muscular systems in vertebrates are controlled through the nervous system although some muscles (such as the cardiac muscle) can be completely autonomous ...

  5. Repressilator - Wikipedia

    en.wikipedia.org/wiki/Repressilator

    Repressilator. The repressilator is a genetic regulatory network consisting of at least one feedback loop with at least three genes, each expressing a protein that represses the next gene in the loop. [ 1] In biological research, repressilators have been used to build cellular models and understand cell function.

  6. Human musculoskeletal system - Wikipedia

    en.wikipedia.org/wiki/Human_musculoskeletal_system

    The musculoskeletal system provides form, support, stability, and movement to the body. It is made up of the bones of the skeleton, muscles, cartilage, [1] tendons, ligaments, joints, and other connective tissue that supports and binds tissues and organs together. The musculoskeletal system's primary functions include supporting the body ...

  7. Silencer (genetics) - Wikipedia

    en.wikipedia.org/wiki/Silencer_(genetics)

    The lac operon in the prokaryote E. coli consists of genes that produce enzymes to break down lactose. Its operon is an example of a prokaryotic silencer. The three functional genes in this operon are lacZ, lacY, and lacA. [6] The repressor gene, lacI, will produce the repressor protein LacI which is under allosteric regulation.

  8. Benno Müller-Hill - Wikipedia

    en.wikipedia.org/wiki/Benno_Müller-Hill

    Benno Müller-Hill (5 February 1933 – 11 August 2018) [1] was a German biologist and author. Together with Walter Gilbert, Müller-Hill purified the lac repressor, the first genetic control protein to be isolated. [2] Müller-Hill has lectured widely and written books on the misuse of science by the Nazis. He was a professor of Genetics at ...

  9. Cis-regulatory element - Wikipedia

    en.wikipedia.org/wiki/Cis-regulatory_element

    An example of a cis-acting regulatory sequence is the operator in the lac operon. This DNA sequence is bound by the lac repressor, which, in turn, prevents transcription of the adjacent genes on the same DNA molecule. The lac operator is, thus, considered to "act in cis" on the regulation of the nearby genes.