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In genetics, the coefficient of coincidence (c.o.c.) is a measure of interference in the formation of chromosomal crossovers during meiosis. It is generally the case that, if there is a crossover at one spot on a chromosome, this decreases the likelihood of a crossover in a nearby spot. [1] This is called interference.
The Kosambi mapping function was introduced to account for the impact played by crossover interference on recombination frequency. It introduces a parameter C, representing the coefficient of coincidence, and sets it equal to 2r. For loci which are strongly linked, interference is strong; otherwise, interference decreases towards zero. [5]
Crossover interference is the term used to refer to the non-random placement of crossovers with respect to each other during meiosis.The term is attributed to Hermann Joseph Muller, who observed that one crossover "interferes with the coincident occurrence of another crossing over in the same pair of chromosomes, and I have accordingly termed this phenomenon ‘interference’."
Full-text aggregator of open access journals and papers (>17,000 journals) from all academic disciplines. Free No [9] Paperity Sp. z o.o. Semantic Scholar: Multidisciplinary: 8,100,000 [10] (200,000,000 metadata [11]) Mostly computer science and biomedical publications. Powered by semantic analysis. Free Semi-free [10] Allen Institute for ...
List of statisticians; List of important publications in statistics; List of scientific journals in statistics; Topic lists. Outline of statistics; List of probability topics; Glossary of probability and statistics; Glossary of experimental design; Notation in probability and statistics; List of probability distributions; List of graphical methods
The trends in topics that have been published in the journal reflect the history of the discipline of genetics. [1] Early issues included many papers on eugenics, particularly under the editorial leadership of the journal's first two editors-in-chief, Paul Popenoe and R. C. Cook. Emphasis on eugenics in the journal declined throughout the 1940s and 1950s as support for the topic waned in the ...
A Missouri couple has been charged with child abuse after police claim they performed a circumcision on a child at their home despite not having the medical training to do so.
Journal of Bioinformatics and Computational Biology; Journal of Biomedical Informatics; Journal of Computational Biology; Journal of Mathematical Biology; Journal of Theoretical Biology; PLOS Computational Biology; Source Code for Biology and Medicine; Statistical Applications in Genetics and Molecular Biology; Statistics in Biosciences