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In genetics, the coefficient of coincidence (c.o.c.) is a measure of interference in the formation of chromosomal crossovers during meiosis. It is generally the case that, if there is a crossover at one spot on a chromosome, this decreases the likelihood of a crossover in a nearby spot. [1] This is called interference.
The Kosambi mapping function was introduced to account for the impact played by crossover interference on recombination frequency. It introduces a parameter C, representing the coefficient of coincidence, and sets it equal to 2r. For loci which are strongly linked, interference is strong; otherwise, interference decreases towards zero. [5]
Crossover interference is the term used to refer to the non-random placement of crossovers with respect to each other during meiosis.The term is attributed to Hermann Joseph Muller, who observed that one crossover "interferes with the coincident occurrence of another crossing over in the same pair of chromosomes, and I have accordingly termed this phenomenon ‘interference’."
Research design Utility Potential analysis Between-group design: Experiment that has two or more groups of subjects each being tested by a different testing factor simultaneously: Student's t-test, Analysis of variance, Mann–Whitney U test: Repeated measures design
In population genetics, the Hill–Robertson effect, or Hill–Robertson interference, is a phenomenon first identified by Bill Hill and Alan Robertson in 1966. [1] It provides an explanation as to why there may be an evolutionary advantage to genetic recombination .
Annual Review of Genomics and Human Genetics; European Journal of Human Genetics; Genetica; Genetics; Genome; Genome Biology; Genome Research; Heredity; Human Genomics and Proteomics; Nature Reviews Genetics; Nucleic Acids Research; PLOS Genetics; Somatic Cell and Molecular Genetics; Trends in Genetics
Huawei Technologies asked a U.S. judge to dismiss much of a federal indictment accusing the Chinese telecommunications company of trying to steal technology secrets from U.S. rivals and misleading ...
This is a list of journals published by Nature Research. These include the flagship Nature journal, the Nature Reviews series (which absorbed the former Nature Clinical Practice series in 2009), the npj series, Scientific Reports and many others.