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A 2007 Cochrane review assessed the side effects of short-term use of pseudoephedrine at recommended doses as a nasal decongestant. [21] It found that pseudoephedrine had a small risk of insomnia and this was the only side effect that occurred at rates significantly different from placebo. [21]
Pseudoephedrine acts indirectly on the adrenergic receptor system, whereas phenylephrine and oxymetazoline are direct agonists. The effects are not limited to the nose, and these medicines may cause hypertension (high blood pressure) through vasoconstriction; it is for this reason that people with hypertension are advised to avoid them. Most ...
Phenylephrine, sold under the brand names Neosynephrine and Sudafed PE among others, is a medication used as a decongestant for uncomplicated nasal congestion in the form of a nasal spray or oral tablet, [5] to dilate the pupil, to increase blood pressure given intravenously in cases of low blood pressure, and to relieve hemorrhoids as a suppository.
[4] [2] [3] Long term use (> 10 days) is not recommended due to a rhinitis medicamentosa when stopped. [ 4 ] [ 5 ] Use is not recommended during pregnancy . [ 2 ] Xylometazoline is in the decongestant and alpha-adrenergic agonist families of medication.
Ephedrine promotes modest short-term weight loss, [24] specifically fat loss, but its long-term effects are unknown. [25] In mice, ephedrine is known to stimulate thermogenesis in the brown adipose tissue, but because adult humans have only small amounts of brown fat, thermogenesis is assumed to take place mostly in the skeletal muscle.
Related: Benadryl for Dogs: Side Effects of Long-Term Use Signs of Benadryl Overdose in Dogs At normal doses, Benadryl is quite safe, but a survey of over 600 dogs (1) found the following signs of ...
6 Potential Long-Term Effects of Ozempic. You may have heard about — or maybe even experienced — the short-term side effects of Ozempic® — such as nausea, vomiting, constipation, and diarrhea.
Rhinitis medicamentosa (or RM, also known as rebound congestion) is a condition of rebound nasal congestion suspected to be brought on by extended use of topical decongestants (e.g., oxymetazoline, phenylephrine, xylometazoline, and naphazoline nasal sprays) and certain oral medications (e.g., sympathomimetic amines and various 2-imidazolines) that constrict blood vessels in the lining of the ...
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