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While women with lupus have higher risk pregnancies, most are successful. [1] Rate of SLE varies between countries from 20 to 70 per 100,000. [2] Women of childbearing age are affected about nine times more often than men. [5] While it most commonly begins between the ages of 15 and 45, a wide range of ages can be affected.
The disease impacts about 1.5 million Americans, but women are nine times more likely to develop lupus than men. And the cause of lupus has largely remained a mystery—until now.
Achieving 1 or greater indicates that Lupkynis is favored over placebo. Additional efficacy data demonstrated the potential to improve renal response regardless of disease progression at diagnosis.
So lupus is characterized by periods of flare-ups and periods of remittance, so treatment is often aimed at preventing flares or limiting how severe they are when they do happen. To help prevent flares, some patients may have to avoid sunlight exposure with hats and long-sleeved clothes.
But again, that work found that just over one in 10 SLE patients (11.4%) experienced a flare following the vaccine, and within that group only about 1% of flares were severe.
Belimumab is primarily used in people with systemic lupus erythematosus. When it was introduced in 2011, it was the first new drug approved to treat lupus in 56 years. [8] Sales rose to $31.2 million in the first quarter of 2012. [37] The total cost for the first year of treatment with belimumab is $28,000. [38]
Lupus erythematosus is a collection of autoimmune diseases in which the human immune system becomes hyperactive and attacks healthy tissues. [1] Symptoms of these diseases can affect many different body systems, including joints , skin , kidneys , blood cells , heart , and lungs .
More than 24 million Americans, by some estimates up to 50 million, have an autoimmune disorder — diseases such as lupus, rheumatoid arthritis, multiple sclerosis and dozens more.
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