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Carbamazepine, sold under the brand name Tegretol among others, is an anticonvulsant medication used in the treatment of epilepsy and neuropathic pain. [ 4 ] [ 1 ] It is used as an adjunctive treatment in schizophrenia along with other medications and as a second-line agent in bipolar disorder .
Many different professionals (physicians, clinical pharmacists, nurses, medical laboratory scientists, etc.) are involved with the various elements of drug concentration monitoring, which is a truly multidisciplinary process. Because failure to properly carry out any one of the components can severely affect the usefulness of using drug ...
Diagnosis is based on clinical and laboratory findings of low serum osmolality and low serum sodium. [13] Urinalysis reveals a highly concentrated urine with a high fractional excretion of sodium (high sodium urine content compared to the serum sodium). [14] A suspected diagnosis is based on a serum sodium under 138.
HLA-B15 allele *15:02 is associated with the severe skin conditions Stevens–Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) caused by carbamazepine drug sensitivity in East Asians. Carriers of the HLA-B15 allele *15:01 (B62) are much more likely to be asymptomatic when infected with SARS-CoV-2 (the virus that causes COVID-19 ).
In medicine and pharmacology, a trough level or trough concentration (C trough) is the concentration reached by a drug immediately before the next dose is administered, [1] [2] often used in therapeutic drug monitoring.
Carbamazepine, or Tegretol, has been used as a mood stabilizer and is accepted treatment for bipolar disorder. [6] Clomiphene (Clomid) for male infertility: clomiphene is approved for female infertility due to ovulatory disorder. Clonidine (Catapres) for ADHD: clonidine is approved and commonly used for the treatment of hypertension. Other off ...
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