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  2. Carbamazepine - Wikipedia

    en.wikipedia.org/wiki/Carbamazepine

    Carbamazepine, sold under the brand name Tegretol among others, is an anticonvulsant medication used in the treatment of epilepsy and neuropathic pain. [ 4 ] [ 1 ] It is used as an adjunctive treatment in schizophrenia along with other medications and as a second-line agent in bipolar disorder .

  3. Primidone - Wikipedia

    en.wikipedia.org/wiki/Primidone

    Primidone, carbamazepine, phenobarbital, and phenytoin are among the most potent hepatic enzyme-inducing drugs in existence, which occurs at therapeutic doses. In fact, people taking these drugs have displayed the highest degree of hepatic-enzyme induction on record. [ 66 ]

  4. List of polysubstance combinations - Wikipedia

    en.wikipedia.org/wiki/List_of_polysubstance...

    Any antiretroviral drug: Black tar heroin: Whoonga, Nyaope [8] Widespread use in South Africa. Whoonga is classically reputed to be a combination of heroin with antiretroviral drugs such as ritonavir and/or efavirenz, often combined with additional drugs such as cannabis or hashish, methamphetamine and/or methaqualone: Any deliriant or diphen ...

  5. ZK-93426 - Wikipedia

    en.wikipedia.org/wiki/ZK-93426

    ZK-93426 (ethyl-5-isopropoxy-4-methyl-beta-carboline-3-carboxylate) is a drug from the beta-carboline family. It acts as a weak partial inverse agonist of benzodiazepine receptors, [1] meaning that it causes the opposite effects to the benzodiazepine class of drugs and has anxiogenic properties, [2] although unlike most benzodiazepine antagonists it is not a convulsant and actually has weak ...

  6. Lurasidone - Wikipedia

    en.wikipedia.org/wiki/Lurasidone

    Lurasidone, sold under the brand name Latuda among others, is an antipsychotic medication used to treat schizophrenia and bipolar depression. [2] It is taken by mouth.. Common side effects include nausea, mild movement problems, sedation, and restlessness. [2]

  7. Phenobarbital - Wikipedia

    en.wikipedia.org/wiki/Phenobarbital

    Phenobarbital may provide a clinical advantage over carbamazepine for treating partial onset seizures. Carbamazepine may provide a clinical advantage over phenobarbital for generalized onset tonic-clonic seizures. [20] The first-line drugs for treatment of status epilepticus are benzodiazepines, such as lorazepam, clonazepam, midazolam, or ...

  8. List of drugs granted breakthrough therapy designation

    en.wikipedia.org/wiki/List_of_drugs_granted...

    Treatment of adults with unresectable or metastatic HER2- positive (IHC 3+) solid tumors who have received prior systemic treatment and have no satisfactory alternative treatment options [2] Eohilia For 12 weeks of treatment in people aged 11 years of age and older with eosinophilic esophagitis [ 2 ]

  9. Cenobamate - Wikipedia

    en.wikipedia.org/wiki/Cenobamate

    The US Food and Drug Administration (FDA) approved cenobamate in November 2019, and granted the application for Xcopri to SK Life Science Inc. [7] [8] [9] [16] In January 2021, the Committee for Medicinal Products for Human Use of the European Medicines Agency adopted a positive opinion, recommending the granting of a marketing authorization. [17]

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