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[25] [26] In cyanobacteria, this enzyme system is housed in a specialized cell called the heterocyst. [27] The production of the nitrogenase complex is genetically regulated, and the activity of the protein complex is dependent on ambient oxygen concentrations, and intra- and extracellular concentrations of ammonia and oxidized nitrogen species ...
The Haber process, [146] also called the Haber–Bosch process, is the main industrial procedure for the production of ammonia. [ 147 ] [ 148 ] It converts atmospheric nitrogen (N 2 ) to ammonia (NH 3 ) by a reaction with hydrogen (H 2 ) using finely divided iron metal as a catalyst:
Ammonium is a modified form of ammonia that has an extra hydrogen atom. It is a positively charged molecular ion with the chemical formula NH + 4 or [NH 4] +.It is formed by the addition of a proton (a hydrogen nucleus) to ammonia (NH 3).
Nitrifying bacteria are present in distinct taxonomical groups and are found in highest numbers where considerable amounts of ammonia are present (such as areas with extensive protein decomposition, and sewage treatment plants). [3]
Nitrogen assimilation is the formation of organic nitrogen compounds like amino acids from inorganic nitrogen compounds present in the environment. Organisms like plants, fungi and certain bacteria that can fix nitrogen gas (N 2) depend on the ability to assimilate nitrate or ammonia for their needs.
Enzymes that catalyse this reaction are called deaminases. In the human body, deamination takes place primarily in the liver; however, it can also occur in the kidney. In situations of excess protein intake, deamination is used to break down amino acids for energy. The amino group is removed from the amino acid and converted to ammonia.
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Glutamine synthetase (GS) (EC 6.3.1.2) [3] is an enzyme that plays an essential role in the metabolism of nitrogen by catalyzing the condensation of glutamate and ammonia to form glutamine: