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  2. Nucleophile - Wikipedia

    en.wikipedia.org/wiki/Nucleophile

    A hydroxide ion acting as a nucleophile in an S N 2 reaction, converting a haloalkane into an alcohol. In chemistry, a nucleophile is a chemical species that forms bonds by donating an electron pair. All molecules and ions with a free pair of electrons or at least one pi bond can act as nucleophiles. Because nucleophiles donate electrons, they ...

  3. RNA hydrolysis - Wikipedia

    en.wikipedia.org/wiki/RNA_hydrolysis

    RNA hydrolysis occurs when the deprotonated 2’ OH of the ribose, acting as a nucleophile, attacks the adjacent phosphorus in the phosphodiester bond of the sugar-phosphate backbone of the RNA. [1] There is a transition state (shown above), where the phosphorus is bonded to five oxygen atoms. [ 2 ]

  4. Non-nucleophilic base - Wikipedia

    en.wikipedia.org/wiki/Non-nucleophilic_base

    Normal bases are also nucleophiles, but often chemists seek the proton-removing ability of a base without any other functions. Typical non-nucleophilic bases are bulky, such that protons can attach to the basic center but alkylation and complexation is inhibited.

  5. Arrow pushing - Wikipedia

    en.wikipedia.org/wiki/Arrow_pushing

    Arrow pushing or electron pushing is a technique used to describe the progression of organic chemistry reaction mechanisms. [1] It was first developed by Sir Robert Robinson.In using arrow pushing, "curved arrows" or "curly arrows" are drawn on the structural formulae of reactants in a chemical equation to show the reaction mechanism.

  6. SN1 reaction - Wikipedia

    en.wikipedia.org/wiki/SN1_reaction

    [1] [2] Thus, the rate equation is often shown as having first-order dependence on the substrate and zero-order dependence on the nucleophile. This relationship holds for situations where the amount of nucleophile is much greater than that of the intermediate. Instead, the rate equation may be more accurately described using steady-state kinetics.

  7. Today's Wordle Hint, Answer for #1272 on Thursday, December ...

    www.aol.com/todays-wordle-hint-answer-1272...

    Hints and the solution for today's Wordle on Thursday, December 12.

  8. Threonine protease - Wikipedia

    en.wikipedia.org/wiki/Threonine_protease

    Threonine proteases use the secondary alcohol of their N-terminal threonine as a nucleophile to perform catalysis. [1] [2] The threonine must be N-terminal since the terminal amine of the same residue acts as a general base by polarising an ordered water which deprotonates the alcohol to increase its reactivity as a nucleophile.

  9. Daniel Jones shares emotional goodbye message to Giants fans ...

    www.aol.com/sports/daniel-jones-shares-emotional...

    Daniel Jones spent parts of Thursday's practice with the New York Giants working with the scout team, even lining up at safety during a walkthrough. The sixth-year quarterback was benched this ...