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  2. Anastrozole - Wikipedia

    en.wikipedia.org/wiki/Anastrozole

    Anastrozole, sold under the brand name Arimidex among others, is an antiestrogenic medication used in addition to other treatments for breast cancer. [6] [7] Specifically it is used for hormone receptor-positive breast cancer. [7] It has also been used to prevent breast cancer in those at high risk. [7] It is taken by mouth. [7]

  3. Aromatase inhibitor - Wikipedia

    en.wikipedia.org/wiki/Aromatase_inhibitor

    Aromatase inhibitors (AIs) are a class of drugs used in the treatment of breast cancer in postmenopausal women and in men, [1] [2] and gynecomastia in men. They may also be used off-label to reduce estrogen conversion when supplementing testosterone exogenously. They may also be used for chemoprevention in women at high risk for breast cancer.

  4. Non steroidal aromatase inhibitors - Wikipedia

    en.wikipedia.org/wiki/Non_steroidal_aromatase...

    The elimination half-life of the drug is 12,5 hours and 34-54% of the drug is excreted unchanged in the urine. [23] Anastrozole is administered orally and has a standard daily dose of 1 mg. Anastrozole has good oral bioavailability and is rapidly absorbed. It takes 2–3 hours for the drug to reach maximum serum concentration.

  5. What is Anastrozole? The breast cancer drug that can cut risk ...

    www.aol.com/anastrozole-breast-cancer-drug-cut...

    Trials have shown that the drug reduces breast cancer cases by 49 per cent over 11 years among eligible women, meaning that if just 25 per cent of eligible women in England take up the offer ...

  6. Steroidal aromatase inhibitor - Wikipedia

    en.wikipedia.org/wiki/Steroidal_aromatase_inhibitor

    Steroidal aromatase inhibitors are a class of drugs that are mostly used for treating breast cancer in postmenopausal women. High levels of estrogen in breast tissue increases the risk of developing breast cancer and the enzyme aromatase is considered to be a good therapeutic target when treating breast cancer due to it being involved in the final step of estrogen biosynthetic pathway and also ...

  7. 5 cancer types where screenings save the most lives - AOL

    www.aol.com/5-cancer-types-where-screenings...

    Over a 45-years span — between 1975 and 2020 — improvements in cancer screenings and prevention strategies have reduced deaths from five common cancers more than any advances in treatments ...

  8. Hormonal therapy (oncology) - Wikipedia

    en.wikipedia.org/wiki/Hormonal_therapy_(oncology)

    Tamoxifen is currently first-line treatment for nearly all pre-menopausal women with hormone receptor-positive breast cancer. [1] Raloxifene is another partial agonist SERM which does not seem to promote endometrial cancer, and is used primarily for chemoprevention of breast cancer in high-risk individuals, as well as to prevent osteoporosis. [1]

  9. A 30-year journey. Elacestrant was not McDonnell’s first attempt at bringing a breast cancer drug to market. In 1996, his lab developed a similar drug, etacstil, which was the first oral ...

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