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In mammalian outer hair cells, the varying receptor potential is converted to active vibrations of the cell body. This mechanical response to electrical signals is termed somatic electromotility; [13] it drives variations in the cell's length, synchronized to the incoming sound signal, and provides mechanical amplification by feedback to the traveling wave.
The organ of Corti is located in the scala media of the cochlea of the inner ear between the vestibular duct and the tympanic duct and is composed of mechanosensory cells, known as hair cells. [2] Strategically positioned on the basilar membrane of the organ of Corti are three rows of outer hair cells (OHCs) and one row of inner hair cells ...
Prestin is the motor protein of the outer hair cells of the inner ear of the mammalian cochlea. [5] It is highly expressed in the outer hair cells, and is not expressed in the nonmotile inner hair cells. Immunolocalization shows prestin is expressed in the lateral plasma membrane of the outer hair cells, the region where electromotility occurs ...
The hair follicle is an organ found in mammalian skin. [1] It resides in the dermal layer of the skin and is made up of 20 different cell types, each with distinct functions. The hair follicle regulates hair growth via a complex interaction between hormones, neuropeptides, and immune cells. [1]
The hair cells are the primary auditory receptor cells and they are also known as auditory sensory cells, acoustic hair cells, auditory cells or cells of Corti. The organ of Corti is lined with a single row of inner hair cells and three rows of outer hair cells. The hair cells have a hair bundle at the apical surface of the cell.
It overlies the sensory inner hair cells and electrically-motile outer hair cells of the organ of Corti and during acoustic stimulation stimulates the inner hair cells through fluid coupling, and the outer hair cells via direct connection to their tallest stereocilia.
The structural change after sound exposure in the Hensen's cells were observed by laser scanning confocal microscopy (LSCM), it showed that after sound exposure, the Hensen's cells moved towed the tunnel of Corti, most of the movement were found in the third row of outer hair cells around with outer part rotates, furthermore, the movement often ...
Hensen's cells, Deiter's cells, and outer hair cells make up the outer tunnel and are mainly responsible for allowing hair cells to function. [1] Hensen's cells are columnar in shape, have many phagosomes in their cytoplasm and contain lipid droplets that correlate with the extent of their innervation.