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The salt substitute used was 25% potassium chloride and 75% sodium chloride. A 2022 Cochrane review of 26 trials involving salt substitutes reported their use probably slightly reduces blood pressure, non-fatal stroke, non-fatal acute coronary syndrome and heart disease death in adults compared to use of regular table salt. [9]
The well-known effect of sodium on blood pressure can be explained by comparing blood to a solution with its salinity changed by ingested salt. Artery walls are analogous to a selectively permeable membrane , and they allow solutes, including sodium and chloride, to pass through (or not), depending on osmosis .
A low sodium diet has a useful effect to reduce blood pressure, both in people with hypertension and in people with normal blood pressure. [7] Taken together, a low salt diet (median of approximately 4.4 g/day – approx 1800 mg sodium) in hypertensive people resulted in a decrease in systolic blood pressure by 4.2 mmHg, and in diastolic blood pressure by 2.1 mmHg.
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Foods high in fiber generally are a source of magnesium. [35] The recommended magnesium intake for adults range from 360 mg to 420 mg depending on age and gender. [35] Epsom salt; Nuts and seeds (e.g., pumpkin seeds, almonds, peanuts) [34] Dark leafy greens (e.g., spinach) [34] Beans [34] Fortified cereals
A 2020 study found that the DASH diet helped a group of people 65 and older struggling with obesity reduce body fat while a 2021 meta-analysis conducted by the National Institute of Health (NIH ...
Reduced salt intake also results in a small but statistically significant reduction in blood pressure. [19] [26] Left ventricular hypertrophy (cardiac enlargement): "Evidence suggests that high salt intake causes left ventricular hypertrophy. This is a strong risk factor for cardiovascular disease, independently of blood pressure effects."
[2] [3] By mouth they are used to treat and prevent low blood calcium, osteoporosis, and rickets. [1] By injection into a vein they are used for low blood calcium that is resulting in muscle spasms and for high blood potassium or magnesium toxicity. [2] [4] Common side effects include constipation and nausea. [1]
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