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As defined, acute inflammation is an immunovascular response to inflammatory stimuli, which can include infection or trauma. [25] [26] This means acute inflammation can be broadly divided into a vascular phase that occurs first, followed by a cellular phase involving immune cells (more specifically myeloid granulocytes in the acute setting). [25]
There are six distinctive morphological patterns of necrosis: [7] Coagulative necrosis is characterized by the formation of a gelatinous (gel-like) substance in dead tissues in which the architecture of the tissue is maintained, [7] and can be observed by light microscopy.
Mesangial proliferative glomerulonephritis (MesPGN) is a morphological pattern characterized by a numerical increase in mesangial cells and expansion of the extracellular matrix within the mesangium of the glomerulus. [1] The increase in the number of mesangial cells can be diffuse or local and immunoglobulin and/or complement deposition can ...
Different diseases are associated with coagulative necrosis, including acute tubular necrosis and acute myocardial infarction. [2] Coagulative necrosis can also be induced by high local temperature; it is a desired effect of treatments such as high intensity focused ultrasound applied to cancerous cells. [3]
Inflammation of the lymphatic vessels is known as lymphangitis. [2] ... acute infection (e.g., bacterial, ... These morphological patterns are never pure. Thus ...
Acute pyelonephritis is an exudative purulent localized inflammation of the renal pelvis (collecting system) and kidney. The kidney parenchyma presents in the interstitium abscesses (suppurative necrosis), consisting in purulent exudate (pus): neutrophils, fibrin, cell debris and central germ colonies (hematoxylinophils). Tubules are damaged by ...
Glomerulonephritis (GN) is a term used to refer to several kidney diseases (usually affecting both kidneys). Many of the diseases are characterised by inflammation either of the glomeruli or of the small blood vessels in the kidneys, hence the name, [1] but not all diseases necessarily have an inflammatory component.
It is the acute inflammation of the bronchi, accompanied by inflamed patches in the nearby lobules of the lungs. [1] It is often contrasted with lobar pneumonia; but, in clinical practice, the types are difficult to apply, as the patterns usually overlap. [2] Bronchopneumonia (lobular) often leads to lobar pneumonia as the infection progresses.