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About 60% of the metronidazole is metabolized by oxidation to the main metabolite hydroxymetronidazole and a carboxylic acid derivative, and by glucuronidation. The metabolites show antibiotic and antiprotozoal activity in vitro. [62] Metronidazole and its metabolites are mainly excreted via the kidneys (77%) and to a lesser extent via the ...
Metronidazole (for vaginitis caused by Trichomonas) Tinidazole (for intestinal infections caused by Giardia lamblia) Miltefosine (for the treatment of visceral and cutaneous leishmaniasis, currently undergoing investigation for Chagas disease)
Antibiotics are used to treat or prevent bacterial infections, [34] and sometimes protozoan infections. (Metronidazole is effective against a number of parasitic diseases). When an infection is suspected of being responsible for an illness but the responsible pathogen has not been identified, an empiric therapy is adopted. [35]
Metronidazole or clindamycin: No Bacteroides species Bacteroides infection No Balantidium coli: Balantidiasis: microscopic examination of stools, or colonoscopy or sigmoidoscopy Tetracycline, metronidazole or iodoquinol: No Bartonella: Bartonellosis: microscopy, serology, and PCR: Antibiotics No Baylisascaris species Baylisascaris infection No ...
Diloxanide is a medication used to treat amoeba infections. [1] In places where infections are not common, it is a second line treatment after paromomycin when a person has no symptoms. [2] For people who are symptomatic, it is used after treatment with metronidazole or tinidazole. [2] It is taken by mouth. [1] Diloxanide generally has mild ...
1960 – metronidazole, the first nitroimidazole; 1961 – ampicillin; 1961 – spectinomycin; 1961 – sulfamethoxazole; 1961 – trimethoprim, the first dihydrofolate reductase inhibitor; 1962 – oxacillin; 1962 – cloxacillin; 1962 – fusidic acid; 1963 – fusafungine; 1963 – lymecycline; 1964 – gentamicin; 1964 – cefalotin, the ...
She told the inquiry infections started to climb from the hospital’s opening in 2015. She said rates of “positive blood cultures” – blood tests that showed the presence of bacteria ...
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