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Performance status In medicine ( oncology and other fields), performance status is an attempt to quantify cancer patients ' general well-being and activities of daily life. This measure is used to determine whether they can receive chemotherapy , whether dose adjustment is necessary, and as a measure for the required intensity of palliative care .
The Eastern Cooperative Oncology Group (ECOG) began in 1955 as one of the first publicly funded cooperative groups to perform multi-center clinical trials for cancer research. [1] A cooperative group in oncology constitutes a large network of private and public medical institutions developing protocols for cancer treatments.
Zubrod's name is also connected to a widely used assessment scale for performance of cancer patients, the Performance Status of the Eastern Cooperative Oncology Group (ECOG) for Patients with Cancer (Zubrod scale).
There were four factors found to have independent prognostic relevance: age, performance status, LDH, and white blood cell count (WBC). [4] The point values are assigned as follows: 0 points: Age less than 50 years, ECOG performance status of 0–1, LDH less than 0.67 of the upper limit of normal, or WBC of less than 6,700 cells/mcl
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Patients with a global deterioration of health status requiring discontinuation of treatment without objective evidence of disease progression at that time should be classified as having “symptomatic deterioration”. Every effort should be made to document the objective progression even after discontinuation of treatment.
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