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Aspirin is also used long-term to help prevent further heart attacks, ischaemic strokes, and blood clots in people at high risk. [10] For pain or fever, effects typically begin within 30 minutes. [10] Aspirin works similarly to other NSAIDs but also suppresses the normal functioning of platelets. [10] One common adverse effect is an upset ...
The most commonly reported side effects of medications used for weight loss are nausea and constipation, but gallbladder and pancreatic disease are also reported. ... Women turn to weight loss ...
Low-dose, long-term aspirin use irreversibly blocks the formation of thromboxane A 2 in platelets, producing an inhibitory effect on platelet aggregation. [13] This effect is mediated by the irreversible blockage of COX-1 in platelets, since mature platelets don't express COX-2.
For healthy, younger adults with an increased risk of heart attack or stroke, daily aspirin could have a modest benefit, though experts still recommend weighing it against the risk of bleeding.
But clinical trials are artificial environments: In the real world, 37% of people using a GLP-1 drug for either diabetes or weight loss had quit a year after starting, according to 2024 research ...
A transient ischemic attack (TIA), commonly known as a mini-stroke, is a temporary (transient) stroke with noticeable symptoms that end within 24 hours. A TIA causes the same symptoms associated with a stroke, such as weakness or numbness on one side of the body, sudden dimming or loss of vision, difficulty speaking or understanding language or slurred speech.
(FYI: Wegovy is FDA-approved for long-term weight management, while Ozempic is FDA-approved to treat type 2 diabetes but often prescribed off-label for medical weight loss.)
Risk of adverse advents such as bleeding or gastrointestinal side effects is relatively high with daily aspirin therapy. Even a 81 mg daily aspirin regimen for cardiovascular benefits has been shown to increase risk of long-term bleeding, [27] so the significantly higher aspirin doses used for maintenance therapy are of some concern. [19]