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Young et al first demonstrated in 2002 that teeth could be regenerated from cells. [4] The first clinical trial on tooth regeneration started in 2023 in Japan, for a medicine stimulating tooth regrowth by inhibition of USAG-1. [5] [6] [7]
A 2023 paper published in Regenerative Therapy decries the lack of treatments available for tooth regrowth, but highlights how the anti-USAG-1 antibody treatment in mice could offer “a ...
The history of dental treatments dates back to thousands of years. [1] [2] The scope of this article is limited to the pre-1981 history.The earliest known example of dental caries manipulation is found in a Paleolithic man, dated between 14,160 and 13,820 BP. [3]
In 1833 French chemist Anselme Payen was the first to discover an enzyme, diastase. In 1834, François Mothes and Joseph Dublanc created a method to produce a single-piece gelatin capsule that was sealed with a drop of gelatin solution. In 1853 Alexander Wood was the first physician that used hypodermic needle to dispense drugs via Injections.
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Block Drug Company was a pharmaceutical company based in Jersey City, New Jersey, United States, that specialized in dental care products.Its most popular products included Polident denture cleanser, Poli-Grip denture adhesive, Dentu-Creme denture toothpaste, Nytol sleeping pill, Tegrin medicated shampoo for psoriasis, Lava hand soaps (acquired from Procter & Gamble), Beano and Phazyme anti ...
A person's baby teeth are known to contain stem cells that can be used for regeneration of the dental pulp after a root canal treatment or injury. These cells can also be used to repair damage from periodontitis, an advanced form of gum disease that causes bone loss and severe gum recession.