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There are five types of stem cells, and MSC's are multi-potent, meaning they are cells that have the ability to develop into more than one type of specialized cell. Mesenchymal stem cells were originally discovered and studied as fibroblast-colony-forming cells in guinea-pig bone marrow and spleen cells by Friedenstein in the 1970s. [8]
Stem-cell therapy uses stem cells to treat or prevent a disease or condition. [1] As of 2024, the only FDA-approved therapy using stem cells is hematopoietic stem cell transplantation. [2] [3] This usually takes the form of a bone marrow or peripheral blood stem cell transplantation, but the cells can also be derived from umbilical cord blood.
A bone marrow transplant, also called a stem cell transplant, restores blood stem cells for people who’ve undergone chemotherapy or radiation therapy for cancer, blood disorders, or autoimmune ...
Articular cartilage stem cell paste grafting was initially described by Kevin R. Stone M.D., a San Francisco-based orthopedic surgeon, in 1997 . The technique was devised in response to reports that many of the contemporary cartilage restoration procedures lead to the development of fibrocartilage, not true hyaline articular cartilage. Knowing ...
Alimorad Farshchian (born April 2, 1962) is an Iranian-born American medical doctor, medical author, and philanthropist. He is the founding director of The Center for Regenerative Medicine, which opened in 2000 in order to pursue pioneering regimens in the treatment of arthritis and other autoimmune diseases.
In 1997, Osiris began a multi-million dollar research and licensing arrangement with Novartis, which acquired 8% of the company.It dedicated 65 employees to develop stem cell treatments for bone and cartilage disorders, including underwriting the cost of clinical trials, an arrangement that lasted until at least 1999.
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