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The scorpion is perceived both as an embodiment of evil and a protective force such as a dervish's powers to combat evil. [10] In another context, the scorpion portrays human sexuality. [10] Scorpions are used in folk medicine in South Asia, especially in antidotes for scorpion stings. [10]
The 'scorpion sting craze' has also increased in India with decreasing availability of other drugs and alcohol available to youth. [6] Young people are reportedly flocking to highway sides where they can purchase scorpion stings that after several minutes of intense pain, supposedly produce a six- to eight-hour feeling of wellbeing.
A scorpion sting is an injury caused by the stinger of a scorpion resulting in the medical condition known as scorpionism, which may vary in severity. The anatomical part of the scorpion that delivers the sting is called a "telson". In typical cases, scorpion stings usually result in pain, paresthesia, and variable swelling.
Chlorotoxin is a 36-amino acid peptide found in the venom of the deathstalker scorpion (Leiurus quinquestriatus) which blocks small-conductance chloride channels. [2] The fact that chlorotoxin binds preferentially to glioma cells has allowed the development of methods for the treatment and diagnosis of several types of cancer.
Cll1 is a long chain neuropeptide belonging to the scorpion toxin superfamily. Cll1 is classified as a member of the beta-toxin subfamily. [3] The global secondary structure of Cll1 is similar to that of other scorpion beta-toxins, including the alpha-helix, triple stranded antiparallel beta-sheet, and the four disulfide bridges.
Thus, this protein emerges as a strong candidate for the production of antiserum to be used in the treatment of scorpion stings. The nontoxic recombinant protein can induce a level of circulating antibodies sufficient to neutralize the toxic effects of Tityus toxins and is a good candidate for use in the production of a new generation of ...
Charybdotoxin (ChTX) is a 37 amino acid neurotoxin from the venom of the scorpion Leiurus quinquestriatus hebraeus (deathstalker) that blocks calcium-activated potassium channels. [2] This blockade causes hyperexcitability of the nervous system. It is a close homologue of agitoxin and both toxins come from Leiurus quinquestriatus hebraeus.
Cn2 is a neurotoxin named after and derived from the Centruroides noxius scorpion, which originates from and is endemic in the state of Nayarit, Western Mexico. [1] This scorpion produces a venom in which the Cn2 toxin is the most abundant component; it comprises approximately 6.8% of the scorpion venom.