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MCF-7 cells. MCF-7 is a breast cancer cell line isolated in 1970 from a 69-year-old woman. [1] MCF-7 is the acronym of Michigan Cancer Foundation-7, referring to the institute in Detroit where the cell line was established in 1973 by Herbert Soule and co-workers. [2] The Michigan Cancer Foundation is now known as the Barbara Ann Karmanos Cancer ...
The E-SCREEN cell proliferation assay is performed with the human MCF-7 breast cancer cell line, an established estrogenic cell line that endogenously expresses ERα. [ 1 ] [ 3 ] [ 4 ] Human MCF-7 are cultivated in Dulbecco’s modified Eagle’s medium (DMEM) with fetal bovine serum (FBS) and phenol red as buffer tracer (culture medium), at 37 ...
T-47D cells can be implanted into immunodeficient mice, forming xenografts that can undergo drug testing with corresponding receptor status and angiogenesis changes. The cells have been noted to be extremely resistant to estrogens and antiestrogens, possibly due to inhibition by 5-bromodeoxyuridine and sodium butyrate.
2) T-47D human breast cancer cells (which express very low levels of FFAR4) and MCF-7 cells transfected with the FFAR-1-producing plasmid had increased proliferative responses to oleic acid compared to control cells. [8] [65] 3) The highly selective FFAR4 agonist TUG-891 reduced the proliferation of MCF-7 and MDA-MB-231 cells.
WASHINGTON – President Donald Trump faces a choice ahead of a Feb. 1 target date for his tariffs to begin kicking in: revenue or revenge? He campaigned on a blanket tariff that would generate ...
C-47D C-47B with high-altitude two-speed superchargers replaced by one-speed superchargers after the war. AC-47D Gunship aircraft with three side-firing .30 in (7.62 mm) Minigun machine guns. EC-47D C-47D with equipment for the Airborne Early Warning role; prior to 1962 was designated AC-47D. NC-47D C-47D modified for test roles. RC-47D
A set of rare identical quadruplets can’t stop holding hands — and it's touching to watch. “They’re constantly reaching for each other,” Jonathan Sandhu, the babies’ dad, tells TODAY.com.
The United States Postal Service suspended service for packages arriving from China and Hong Kong, but relented just hours later.