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Adverse reaction reporting is an important component of New Zealand's pharmacovigilance activities. The Centre for Adverse Reactions Monitoring (CARM) in Dunedin is New Zealand's national monitoring centre for adverse reactions. It collects and evaluates spontaneous reports of adverse reactions to medicines, vaccines, herbal products and ...
Adverse drug reaction (ADR), a harmful unintended result caused by taking medication; Combined drug intoxication; Conservative management; Drug-drug interaction (DDI), an alteration of the action of a drug caused by the administration of other drugs; Paradoxical reaction, an effect of a substance opposite to what would usually be expected
Mechanisms underlying the cause of reactogenicity symptoms. In clinical trials, reactogenicity is the capacity of a vaccine to produce common, "expected" adverse reactions, especially excessive immunological responses and associated signs and symptoms, including fever and sore arm at the injection site.
Another word for muscle pain, myalgia affects muscles, ligaments, tendons, and connective tissues. In clinical trials of Cialis, one to four percent of men reported muscle pain as an adverse effect.
Adverse reactions, such as allergic reactions to drugs, even when unexpected by pharmacotherapists, are also classified as iatrogenic. The evolution of antibiotic resistance in bacteria is iatrogenic as well. [9] Bacterial strains resistant to antibiotics have evolved in response to the over prescription of antibiotic drugs. [10]
Adverse drug reaction is effects arising when drug given even in therapeutic dose either immunologically mediated reaction or pharmacologically mediated adverse response or idiosyncratic reaction due to the peculiarities of individual. Adverse event (AE) is a side effect occurring with a drug. By definition, the causal relationship between the ...
Paradoxical reaction to a drug; that is, a reaction that is the opposite to the intended purpose of the drug. An example is benzodiazepines , a class of psychoactive drugs considered minor tranquilizers with varying hypnotic, sedative, anxiolytic , anticonvulsant , and muscle relaxant effects; paradoxically they may also create hyperactivity ...
An allergic reaction will not occur on the first exposure to a substance. The first exposure allows the body to create antibodies and memory lymphocyte cells for the antigen. However, drugs often contain many different substances, including dyes, which could cause allergic reactions. This can cause an allergic reaction on the first ...