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Prentice et al [5] predicted that the emerging molecular genetics field would ultimately provide a way to test between the adaptive 'thrifty gene' idea and the non-adaptive 'drifty gene' idea because it would be possible to find signatures of positive selection in the human genome, at genes that are linked to both obesity and type 2 diabetes ...
Both genetic drift and genetic draft are random evolutionary processes, i.e. they act stochastically and in a way that is not correlated with selection at the gene in question. Drift is the change in the frequency of an allele in a population due to random sampling in each generation. [9]
The main feature of this hypothesis is that the current pattern of obesity does not suggest that obesity has been under strong positive selection for a protracted period of time. It is argued instead that the obesity comes about because of genetic drift in the genes controlling the upper limit on our body fatness. Such drift may have started ...
In this study, however, we found a clear genetic trigger for obesity,” said lead study author Dr. Mattia Frontini, British Heart Foundation senior fellow and an associate professor in cellular ...
Like many other medical conditions, obesity is the result of an interplay between environmental and genetic factors. [2] [3] Studies have identified variants in several genes that may contribute to weight gain and body fat distribution; although, only in a few cases are genes the primary cause of obesity.
Genetic drift, also known as random genetic drift, allelic drift or the Wright effect, [1] is the change in the frequency of an existing gene variant in a population due to random chance. [ 2 ] Genetic drift may cause gene variants to disappear completely and thereby reduce genetic variation . [ 3 ]
The implication that genetics are wholly to blame for obesity pushed commenters to rage. The cause of obesity is lifestyle, the Internet roared, setting up a two-sided debate that is still ...
BMI is a measurement of body fat based on a person’s height and weight. An overweight BMI is between 25 and 29.9. ... Certain genetic conditions can also cause obesity. For example, Prader-Willi ...