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2. Dimethyl fumarate - Wikipedia

   en.wikipedia.org/wiki/Dimethyl_fumarate

   The first medical use of fumaric acid was described in 1959 by Walter Schweckendiek, a German chemist, [15] and was a topical formulation for psoriasis. The Swiss company Fumapharm eventually brought Fumaderm, an oral formulation of dimethyl fumarate (along with some monoesters) to market for psoriasis in Germany in 1994.

3. Fumaric acid - Wikipedia

   en.wikipedia.org/wiki/Fumaric_acid

   Fumaric acid or trans-butenedioic acid is an organic compound with the formula HO 2 CCH=CHCO 2 H. A white solid, fumaric acid occurs widely in nature. It has a fruit-like taste and has been used as a food additive. Its E number is E297. [3] The salts and esters are known as fumarates. Fumarate can also refer to the C 4 H 2 O 2− 4 ion (in ...

4. Psoriasis - Wikipedia

   en.wikipedia.org/wiki/Psoriasis

   Another set of treatments for moderate to severe psoriasis are fumaric acid esters (FAE), which may be similar in effectiveness to methotrexate. [108] Apremilast (Otezla, Celgene) is an oral small-molecule inhibitor of the enzyme phosphodiesterase 4, which plays an important role in chronic inflammation associated with psoriasis. [109]

5. Which Psoriasis Treatment is Right for You? - AOL

   www.aol.com/psoriasis-treatment-203600074.html

   Treatment Options for Psoriasis. Medical treatment options for psoriasis generally fall into a few different categories. Topical therapies. These are your creams or lotions (corticosteroids ...

6. Maleate isomerase - Wikipedia

   en.wikipedia.org/wiki/Maleate_isomerase

   Maleate isomerase can be used to produce fumaric acid, an important building block material for polymerization and esterification reactions, from the isomerization of maleic acid. [7] Maleic acid is produced from maleic anhydride. [7] Maleic acid can also be converted into fumaric acid by thermal or catalytic cis–trans isomerization.

7. ATC code D05 - Wikipedia

   en.wikipedia.org/wiki/ATC_code_D05

   ATC code D05 Antipsoriatics is a therapeutic subgroup of the Anatomical Therapeutic Chemical Classification System, a system of alphanumeric codes developed by the World Health Organization (WHO) for the classification of drugs and other medical products.