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For example, venlafaxine works alongside its primary metabolite O-desmethylvenlafaxine to strongly inhibit serotonin and norepinephrine reuptake in the brain. The evidence also suggests that dopamine and norepinephrine behave in a co-transportational manner, due to the inactivation of dopamine by norepinephrine reuptake in the frontal cortex ...
New drugs to treat debilitating menopause symptoms — namely hot flashes — are finally on the market or are in development. ... pain medication gabapentin or an antidepressant sold as Effexor ...
Venlafaxine, sold under the brand name Effexor among others, is an antidepressant medication of the serotonin–norepinephrine reuptake inhibitor (SNRI) class. [ 6 ] [ 9 ] It is used to treat major depressive disorder , generalized anxiety disorder , panic disorder , and social anxiety disorder . [ 9 ]
Desvenlafaxine is a synthetic form of the isolated major active metabolite of venlafaxine, and is categorized as a serotonin-norepinephrine reuptake inhibitor (SNRI). When most normal metabolizers take venlafaxine, approximately 70% of the dose is metabolized into desvenlafaxine, so the effects of the two drugs are expected to be very similar. [18]
Menopause may be a more familiar concept to most. It occurs when a woman hasn’t had her menstrual cycle for 12 consecutive months. The average age for menopause in the U.S. is around 52 years old.
In a 2022 position statement, the North American Menopause Society said hormone therapy has more benefits than risks for women younger than 60 and within 10 years of menopause, unless they have ...
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