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The channels are formed by concentric layers called lamellae, which are approximately 50 μm in diameter. The Haversian canals surround blood vessels and nerve cells throughout bones and communicate with osteocytes (contained in spaces within the dense bone matrix called lacunae) through connections called canaliculi.
Each osteon consists of concentric layers, or lamellae, of compact bone tissue that surround a central canal, the Haversian canal. The Haversian canal contains the bone's blood supplies. The boundary of an osteon is the cement line. Each Haversian canal is surrounded by varying number (5-20) of concentrically arranged lamellae of bone matrix.
Within the bone itself, the haversian canals become blocked with scar tissue, and the bone becomes surrounded by thickened periosteum. [ citation needed ] Due to the avascular nature of this bone, antibiotics which travel to sites of infection via the bloodstream poorly penetrate these tissues, hence the difficulty in treating chronic ...
Havers' thesis. Clopton Havers (24 February 1657 – April 1702) was an English physician who did pioneering research on the microstructure of bone. He is believed to have been the first person to observe and almost certainly the first to describe what are now called Haversian canals and Sharpey's fibres.
Bone canaliculi are microscopic canals between the lacunae of ossified bone. The radiating processes of the osteocytes (called filopodia) project into these canals. These cytoplasmic processes are joined together by gap junctions. Osteocytes do not entirely fill up the canaliculi.
Volkmann's canals, also known as perforating holes or channels, are anatomic arrangements in cortical bones that allow blood vessels to enter the bones from periosteum. They interconnect the Haversian canals (running inside osteons ) with each other and the periosteum.
An osteocyte, an oblate shaped type of bone cell with dendritic processes, is the most commonly found cell in mature bone. It can live as long as the organism itself. [1] The adult human body has about 42 billion of them. [2] Osteocytes do not divide and have an average half life of 25 years.
The heart's cardiac skeleton comprises four dense connective tissue rings that encircle the mitral and tricuspid atrioventricular (AV) canals and extend to the origins of the pulmonary trunk and aorta. This provides crucial support and structure to the heart while also serving to electrically isolate the atria from the ventricles. [1]