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Screenshot of the CAS Common Chemistry database with information about caffeine ().. A CAS Registry Number [1] (also referred to as CAS RN [2] or informally CAS Number) is a unique identification number, assigned by the Chemical Abstracts Service (CAS) in the US to every chemical substance described in the open scientific literature, in order to index the substance in the CAS Registry.
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Chemical Safety Reports are the main end point for data assessment under REACH (the European Community Regulation on chemicals and their safe use, concerning the Registration, Evaluation, Authorisation and Restriction of Chemical substances [4]) in which hazard and exposure data are considered together to assess the risk of a substance. [5]
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The Unique Ingredient Identifier (UNII) is an alphanumeric identifier linked to a substance's molecular structure or descriptive information and is generated by the Global Substance Registration System (GSRS) of the Food and Drug Administration (FDA).