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After ovulation and during the luteal phase, the uterine endometrium is in the secretory phase which is characterized by the production of progesterone from the growing corpus luteum. Progesterone inhibits endometrial proliferation, and preserves uterine tissue in preparation for fertilized egg implantation.
The corpus luteum develops from an ovarian follicle during the luteal phase of the menstrual cycle or oestrous cycle, following the release of a secondary oocyte from the follicle during ovulation. The follicle first forms a corpus hemorrhagicum before it becomes a corpus luteum, but the term refers to the visible collection of blood, left ...
Ovulation is an important part of the menstrual cycle in female vertebrates where the egg cells are released from the ovaries as part of the ovarian cycle. In female humans ovulation typically occurs near the midpoint in the menstrual cycle and after the follicular phase. Ovulation is stimulated by an increase in luteinizing hormone (LH).
Next the egg gets released, and the area from which the egg developed becomes the corpus luteum. This marks the beginning of the luteal phase, which typically lasts for 10 to 14 days.
The secretory phase is the final phase of the uterine cycle and it corresponds to the luteal phase of the ovarian cycle. During the secretory phase, the corpus luteum produces progesterone, which plays a vital role in making the endometrium receptive to the implantation of a blastocyst (a fertilized egg, which has begun to grow). [56]
Ovulation and the corpus luteum [ edit ] By the end of the follicular (or proliferative) phase of the thirteenth day of the menstrual cycle, the cumulus oophorus layer of the preovulatory follicle will develop an opening, or stigma , and excrete the oocyte with a complement of cumulus cells in a process called ovulation .
This phase is characterized by the activity of the corpus luteum, which produces progesterone. The signs of estrogen stimulation subside and the corpus luteum starts to form. The uterine lining begins to appear. In the absence of pregnancy, the diestrus phase (also termed pseudopregnancy) terminates with the regression of the corpus luteum. The ...
The early embryo has 1–2 weeks in order to produce sufficient hCG in order to stabilize the endometrial lining to allow for blastocyst attachment. The dramatic increase in trophoblastic and corpus luteal hCG synthesis signals both blastocyst [5] and corpus luteal [6] production of P4, crucial for the maintenance of the endometrium.