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About 90% of cases of herpes encephalitis are caused by herpes simplex virus-1 (HSV-1), the same virus that causes cold sores. According to a 2006 estimate, 57% of American adults were infected with HSV-1, [ 3 ] which is spread through droplets, casual contact and sometimes sexual contact, though most infected people never have cold sores.
Lack of testing resources may prevent accurate diagnosis. [1] [4] Test results specific to certain viruses include: [1] For herpes simplex virus encephalitis, a CT scan may show low-density lesions in the temporal lobe. These lesions usually appear 3 to 5 days after the start of the infection.
In 2015, encephalitis was estimated to have affected 4.3 million people and resulted in 150,000 deaths worldwide. [4] [3] Herpes simplex encephalitis has an incidence of 2–4 per million of the population per year. [36]
HSV-1 can lead to potentially fatal cases of herpes simplex encephalitis. [84] Herpes simplex viruses have also been studied in the central nervous system disorders such as multiple sclerosis, but research has been conflicting and inconclusive. [85] Following a diagnosis of genital herpes simplex infection, patients may develop an episode of ...
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In dermatopathology, the Tzanck test, also Tzanck smear, is scraping of an ulcer base to look for Tzanck cells. It is sometimes also called the chickenpox skin test and the herpes skin test. It is a simple, low-cost, and rapid office based test. [1] Tzanck cells (acantholytic cells) are found in: Herpes simplex [2] Varicella and herpes zoster
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