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Common side effects (1 to 10% of patients) include constipation, abdominal pain, nausea, and acid reflux. [4] Use is not recommended during pregnancy or in those with poor kidney function . [ 5 ] Alendronic acid works by decreasing the activity of cells that break down bone.
Potential risks: Some negative side effects like muscle cramps, facial swelling, and bloating have been reported in relation to medication interactions, as well as for some people with existing ...
A lack of exposure to sunlight, the natural process of aging, and high levels of body fat can all contribute to vitamin D deficiency, which can lead to osteoporosis, bone and joint pain, and ...
As with many supplements, there is a possible risk of mild side effects, especially in high doses. These include stomach upset, headache, or skin flushing. NAD injections may cause temporary ...
A link in mice between the concentration of myostatin in the prenatal environment and the strength of offspring's bones, partially counteracting the effects of osteogenesis imperfecta (brittle bone disease) has been found. [59] Osteogenesis imperfecta is due to a mutation that causes the production of abnormal Type I collagen.
The long side-chain (R 2 in the diagram) determines the chemical properties, the mode of action and the strength of bisphosphonate drugs. The short side-chain (R 1), often called the 'hook', mainly influences chemical properties and pharmacokinetics. See nitrogenous and non-nitrogenous sections in Mechanism of action below.
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