Search results
Results from the WOW.Com Content Network
The hook effect refers to the prozone phenomenon, also known as antibody excess, or the postzone phenomenon, also known as antigen excess. It is an immunologic phenomenon whereby the effectiveness of antibodies to form immune complexes can be impaired when concentrations of an antibody or an antigen are very high.
Retrieved from "https://en.wikipedia.org/w/index.php?title=High_dose_hook_effect&oldid=548749569"This page was last edited on 4 April 2013, at 23:54
High-dose chemotherapy (HDC) is a regimen of chemotherapy medicines given at larger dosages. This therapeutic strategy is used to treat some cancers, especially those that are aggressive or have a high chance of coming back. With increased doses of chemotherapy chemicals administered to the body, HDC seeks to optimize the death of cancer cells.
The study met its primary and secondary endpoints, demonstrating that treatment with low-dose interleukin-2 is safe and well-tolerated in patients with Alzheimer’s. Also Read: EXCLUSIVE: Coya ...
A hook effect is commonly observed with high concentrations of PROTACs due to the bifunctional nature of the degrader. [15] Currently, pVHL and CRBN have been used in preclinical trials as E3 ligases. [15] However, there still remains hundreds of E3 ligases to be explored, with some giving the opportunity for cell specificity.
Recent research has found that high-dose prescription amphetamines, often used to treat ADHD, are linked to a seriously heightened risk of psychosis. ... “This is a rare but serious side effect ...
Get AOL Mail for FREE! Manage your email like never before with travel, photo & document views. Personalize your inbox with themes & tabs. You've Got Mail!
Taking a high dose of ADHD drugs is linked to more than five times greater risk of developing psychosis or mania, according to a new study published Thursday in the American Journal of Psychiatry.