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Calculated osmolarity = 2 Na + Glucose + Urea (all in mmol/L) As Na+ is the major extracellular cation, the sum of osmolarity of all other anions can be assumed to be equal to natremia, hence [Na+]x2 ≈ [Na+] + [anions] To calculate plasma osmolality use the following equation (typical in the US): = 2[Na +
Erythrocyte fragility refers to the propensity of erythrocytes (red blood cells, RBC) to hemolyse (rupture) under stress. It can be thought of as the degree or proportion of hemolysis that occurs when a sample of red blood cells are subjected to stress (typically physical stress, and most commonly osmotic and/or mechanical stress). Depending on ...
When a measure of serum solutes is calculated, it is often done in units of osmolarity. While it is possible to convert between osmolality and osmolarity, [6] thereby deriving a more mathematically correct osmol gap calculation, in actual clinical practice this is not done. This is because the difference in absolute value of these two ...
As the osmolyte concentration in fish cells scales linearly with pressure and therefore depth, osmolytes have been used to calculate the maximum depth where a fish can survive. Fish cells reach a maximum concentration of osmolytes at depths of approximately 26,900 feet (8,200 meters), with no fish ever being observed beyond 27,349 feet (8,336 ...
η(δ) = viscosity of blood in the wall plasma release-cell layering; r = radius of the blood vessel; δ = distance in the plasma release-cell layer; Blood resistance varies depending on blood viscosity and its plugged flow (or sheath flow since they are complementary across the vessel section) size as well, and on the size of the vessels.
Osmoregulation is the active regulation of the osmotic pressure of an organism's body fluids, detected by osmoreceptors, to maintain the homeostasis of the organism's water content; that is, it maintains the fluid balance and the concentration of electrolytes (salts in solution which in this case is represented by body fluid) to keep the body fluids from becoming too diluted or concentrated.
For cells without a cell wall such as animal cells, if the gradient is large enough, the uptake of excess water can produce enough pressure to induce cytolysis, or rupturing of the cell. When plant cells are in a hypotonic solution, the central vacuole takes on extra water and pushes the cell membrane against the cell wall. Due to the rigidity ...
If plasma osmolarity rises above 290 mOsmol/L, then water will move out of the cell due to osmosis, causing the neuroreceptor to shrink in size. Embedded into the cell membrane are stretch inactivated cation channels (SICs), which when the cell shrinks in size, open and allow positively charged ions, such as Na + and K + ions to enter the cell. [3]