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Syphilis (/ ˈ s ɪ f ə l ɪ s /) is a sexually transmitted infection caused by the bacterium Treponema pallidum subspecies pallidum. [1] The signs and symptoms depend on the stage it presents: primary, secondary, latent or tertiary.
A chancre (/ ˈ ʃ æ ŋ k ər / SHANG-kər) [1] is a painless genital ulcer most commonly formed during the primary stage of syphilis. [2] This infectious lesion forms around 21 days after the initial exposure to Treponema pallidum, the gram-negative spirochaete bacterium causing syphilis, but can range from 10 to 90 days. [2]
In another hopeful development, a shortage that began in early 2023 of the only recommended treatment for syphilis among pregnant women, Pfizer’s Bicillin-LA, has abated.
The first effective treatment for a sexually transmitted infection was salvarsan, a treatment for syphilis. With the discovery of antibiotics , a large number of sexually transmitted infections became easily curable, and this, combined with effective public health campaigns against STIs, led to a public perception during the 1960s and 1970s ...
Syphilis is treatable with antibiotics. However, if left untreated, it can progress through several stages and lead to a wide range of health issues. Houston sees 128% increase in syphilis cases ...
Syphilis rates in Texas continue to climb, alarming healthcare workers who see the highest increases among pregnant people and newborns. A shortage of treatment is complicating efforts to combat it.
Treponema pallidum, formerly known as Spirochaeta pallida, is a microaerophilic, gram-negative, spirochaete bacterium with subspecies that cause the diseases syphilis, bejel (also known as endemic syphilis), and yaws. [1] It is known to be transmitted only among humans and baboons. [2]
The Houston Health Department has reported a syphilis outbreak, with an increase of 128% among women in the city, and a ninefold increase in congenital cases in Houston and the surrounding Harris ...
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