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Technetium-99m (Tc-99m) can be readily detected in the body by medical equipment because it emits 140.5 keV gamma rays (these are about the same wavelength as emitted by conventional X-ray diagnostic equipment), and its half-life for gamma emission is six hours (meaning 94% of it decays to 99 Tc in 24 hours). Besides, it emits virtually no beta ...
Technetium-99 (99 Tc) is an isotope of technetium which decays with a half-life of 211,000 years to stable ruthenium-99, emitting beta particles, but no gamma rays. It is the most significant long-lived fission product of uranium fission, producing the largest fraction of the total long-lived radiation emissions of nuclear waste .
A nuclear pharmacist adds anywhere from 50 - 100 mCi of Na[99m TcO 4] to the reaction vial to make the final product, in the pH range of 3.8 to 8.0. After being allowed to react at room temperature for 15 minutes to ensure maximum labeling of the human albumin with 99m Tc, the kit can then be diluted with sterile normal saline as needed.
Technetium (99m Tc) sestamibi is a lipophilic cation which, when injected intravenously into a patient, distributes in the myocardium proportionally to the myocardial blood flow. Single photon emission computed tomography imaging of the heart is performed using a gamma camera to detect the gamma rays emitted by the technetium-99m as it decays.
Before the development of tracers such as 99m Tc-MAG3, a range of other radiopharmaceuticals were employed. The test was first introduced in 1956, using iodine-131 diodrast . [ 25 ] [ 26 ] Later developments included iodine-131, and then iodine-123 , labelled ortho-Iodohippuric acid (OIH, marketed as Hippuran).
Technetium (99m Tc) exametazime is a radiopharmaceutical sold under the trade name Ceretec, and is used by nuclear medicine physicians for the detection of altered regional cerebral perfusion in stroke [1] and other cerebrovascular diseases.
Technetium (99m Tc) mebrofenin is a diagnostic radiopharmaceutical used for imaging of the liver and the gallbladder. Under the brand name Choletec it is available from Bracco Diagnostic . Supplied as a sterile kit of mebrofenin and dehydrated stannous fluoride .
A Tc-99m pertechnetate solution is being eluted from Mo-99 molybdate bound to a chromatographic substrate. A technetium-99m generator, or colloquially a technetium cow or moly cow, is a device used to extract the metastable isotope 99m Tc of technetium from a decaying sample of molybdenum-99.