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Sodium thiosulfate (sodium thiosulphate) is an inorganic compound with the formula Na 2 S 2 O 3 ·(H 2 O) x. Typically it is available as the white or colorless pentahydrate (x = 5), which is a white solid that dissolves well in water. The compound is a reducing agent and a ligand, and these properties underpin its applications. [2]
Sodium thiosulfate, also spelled sodium thiosulphate, is used as a medication to treat cyanide poisoning, pityriasis versicolor, and to decrease side effects from cisplatin. [ 3 ] [ 4 ] [ 5 ] For cyanide poisoning, it is often used after the medication sodium nitrite and is typically only recommended for severe cases.
Thiosulfate: The evidence for sodium thiosulfate's use is based on animal studies and case reports: the small quantities of cyanide present in dietary sources and in cigarette smoke are normally metabolized to relatively harmless thiocyanate by the mitochondrial enzyme rhodanese (thiosulfate cyanide sulfurtransferase), which uses thiosulfate as ...
Thiosulfate (IUPAC-recommended spelling; sometimes thiosulphate in British English) is an oxyanion of sulfur with the chemical formula S 2 O 2− 3.Thiosulfate also refers to the compounds containing this anion, which are the salts of thiosulfuric acid, such as sodium thiosulfate Na 2 S 2 O 3 and ammonium thiosulfate (NH 4) 2 S 2 O 3.
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The reduction reaction is analogous to the iodine reduction reaction. Treatment of tapwater requires between 0.1 and 0.3 grams of pentahydrated (crystalline) sodium thiosulfate per 10 L of water [citation needed]. Many animals are sensitive to chloramine, and it must be removed from water given to many animals in zoos. [citation needed]
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