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Lipase inhibitors can be found naturally in plants and can also be produced as pharmaceutical drugs.Some lipase inhibitors have been identified in Panax ginseng. [5] [6] Some active compounds with chalcone scaffold found in Glycyrrhiza glabra, Cassia mimosoides, Glycyrrhiza uralensis, Boesenbergia rotunda, apples and Morus alba also had strong effect against lipase.
Weight loss drugs have been developed since the early twentieth century, and many have been banned or withdrawn from the market due to adverse effects, including deaths; other drugs proved ineffective. Although many earlier drugs were stimulants such as amphetamines, in the early 2020s, GLP-1 receptor agonists became popular for weight loss.
Because of the configuration of their glycosidic bonds, galactooligosaccharides largely resist hydrolysis by salivary and intestinal digestive enzymes. [1] Galactooligosaccharides are classified as prebiotics , defined as non-digestible food ingredients as substrate for the host by stimulating the growth and activity of bacteria in the colon.
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