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75387 Ensembl ENSG00000089163 ENSMUSG00000029524 UniProt Q9Y6E7 Q8R216 RefSeq (mRNA) NM_012240 NM_001385733 NM_001385734 NM_001385735 NM_001167691 NM_133760 RefSeq (protein) NP_036372 NP_001161163 NP_598521 Location (UCSC) Chr 12: 120.3 – 120.31 Mb Chr 5: 115.48 – 115.48 Mb PubMed search Wikidata View/Edit Human View/Edit Mouse Sirtuin 4, also known as SIRT4, is a mitochondrial protein ...
As of 2020, about 17.6 million people globally were living with rheumatoid arthritis, an autoimmune disease causing painful inflammation and swelling in joints. Scientists are still not sure as to ...
l-Kynurenine is a metabolite of the amino acid l-tryptophan used in the production of niacin. Kynurenine is synthesized by the enzyme tryptophan dioxygenase , which is made primarily but not exclusively in the liver, and indoleamine 2,3-dioxygenase , which is made in many tissues in response to immune activation. [ 1 ]
William Kaufman published articles in the 1940s that detailed his treatment of arthritis with frequent, high doses of niacinamide. [18] Rudolf Altschul and Abram Hoffer applied large doses of the immediate release form of niacin (Vitamin B 3 ) to treat hypercholesterolemia .
Anserine (β-alanyl-3-methylhistidine) is a dipeptide containing β-alanine and 3-methylhistidine. [1] Anserine is a derivative of carnosine, which has been methylated. [2]Both anserine and carnosine chelate copper. [3]
According to the National Center for Complementary and Integrative Health, there are some studies that support berberine’s weight loss potential, but others had inconclusive outcomes.
Margaret Belle (Oakley) Dayhoff (March 11, 1925 – February 5, 1983) was an American Biophysicist and a pioneer in the field of bioinformatics. [1] Dayhoff was a professor at Georgetown University Medical Center and a noted research biochemist at the National Biomedical Research Foundation, where she pioneered the application of mathematics and computational methods to the field of biochemistry.
“People with malabsorption in their stomach or intestines, such as patients after weight loss surgery or patients with gastrointestinal issues, need robust vitamin supplementation to maintain ...
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