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2. Effect of oxygen on chronic obstructive pulmonary disease

   en.wikipedia.org/wiki/Effect_of_oxygen_on...

   Many people with chronic obstructive pulmonary disease have a low partial pressure of oxygen in the blood and high partial pressure of carbon dioxide.Treatment with supplemental oxygen may improve their well-being; alternatively, in some this can lead to the adverse effect of elevating the carbon dioxide content in the blood (hypercapnia) to levels that may become toxic.

3. Obstructive lung disease - Wikipedia

   en.wikipedia.org/wiki/Obstructive_lung_disease

   Many patients eventually require oxygen supplementation at home. In severe cases that are difficult to control, chronic treatment with oral corticosteroids may be necessary, although this is fraught with significant side effects. COPD is generally irreversible although lung function can partially recover if the patient stops smoking.

4. Chronic obstructive pulmonary disease - Wikipedia

   en.wikipedia.org/wiki/Chronic_obstructive...

   Chronic obstructive pulmonary disease (COPD) is a type of progressive lung disease characterized by chronic respiratory symptoms and airflow limitation. [8] GOLD 2024 defined COPD as a heterogeneous lung condition characterized by chronic respiratory symptoms (dyspnea or shortness of breath, cough, sputum production and/or exacerbations) due to abnormalities of the airways (bronchitis ...

5. US FDA approves Verona Pharma's inhaled COPD therapy - AOL

   www.aol.com/news/us-fda-approves-verona-pharmas...

   The U.S. FDA's assent for the therapy, to be sold under the brand Ohtuvayre, is the company's first and provides a new inhaled non-steroidal treatment for chronic obstructive pulmonary disease.

6. Reactive oxygen species - Wikipedia

   en.wikipedia.org/wiki/Reactive_oxygen_species

   Reactive oxygen species are implicated in cellular activity to a variety of inflammatory responses including cardiovascular disease. They may also be involved in hearing impairment via cochlear damage induced by elevated sound levels , in ototoxicity of drugs such as cisplatin , and in congenital deafness in both animals and humans.

7. Superoxide dismutase - Wikipedia

   en.wikipedia.org/wiki/Superoxide_dismutase

   Reactive oxygen species levels increase with age in these mutant strains and show a similar pattern to the pattern of DNA damage increase with age. Thus it appears that superoxide dismutase plays a substantial role in preserving genome integrity during aging in S. cerevisiae. SOD2 knockout or null mutations cause growth inhibition on ...