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Thiomersal is very toxic by inhalation, ingestion, and in contact with skin (EC hazard symbol T+), with a danger of cumulative effects. It is also very toxic to aquatic organisms and may cause long-term adverse effects in aquatic environments (EC hazard symbol N). [24]
Concerns about thiomersal and vaccines are commonly expressed by anti-vaccine activists. Claims relating to the safety of thiomersal, a mercury-based preservative used in vaccines, are refuted, but still subject to fearmongering, notably claims it could cause neurological disorders such as autism, leading to its removal from most vaccines in the US childhood schedule. [1]
The toxicity of organomercury compounds [1] [2] presents both dangers and benefits. Dimethylmercury in particular is notoriously toxic, but found use as an antifungal agent and insecticide. Merbromin and phenylmercuric borate are used as topical antiseptics, while thimerosal is safely used as a preservative for vaccines and antitoxins. [3]
Formaldehyde, á-tocopheryl hydrogen succinate, polysorbate 80, sodium deoxycholate, thimerosal, ovalbumin: Influenza vaccine Beta-propiolactone, egg protein, neomycin, nonylphenol ethoxylate, polymyxin, thimerosal (multi-dose containers), thimerosal [4] (single-dose syringes) Influenza vaccine
Preservatives prevent the growth of bacteria and fungi, and are more commonly used in vaccines produced as multi-dose vials. They must also be non-toxic in the dose used and not adversely affect the immunogenicity of the vaccine. [29] Thiomersal is the best known and most controversial preservative. It was phased out of UK vaccines between 2003 ...
It’s a safe, effective treatment for metal toxicity, Roach says, but, “It needs to be prescribed by an expert and used in a carefully monitored situation.” ... Some claim thimerosal—a ...
The concentration of thiomersal used in vaccines as an antimicrobial agent ranges from 0.001% (1 part in 100,000) to 0.01% (1 part in 10,000). [69] A vaccine containing 0.01% thiomersal has 25 micrograms of mercury per 0.5 mL dose, roughly the same amount of elemental mercury found in a three-ounce (85 g) can of tuna . [ 69 ]
Human toxicity is, however, hard to avoid with pesticides targeting mammals, such as rodenticides. The risk from toxicity is also distinct from toxicity itself. For instance, the preservative thiomersal used in vaccines is toxic, but the quantity administered in a single shot is negligible.